Updated 2024-10-22
Younger, Longer Science Brief
Decode the genetic, inflammatory, and regenerative levers that keep faces looking rested for longer.
Looking younger than your age is rarely an accident. We review MC1R and FOXO3 gene research, collagen glycation, lifestyle biomarkers, and how regenerative treatments such as PRP facelifts, polynucleotides, and stem-cell therapies fit into a longevity plan.
Decode your biology
Run a longevity panel (lipids, HbA1c, inflammatory markers) plus nutrigenomic testing if possible. Compare your lifestyle habits to FOXO3/MC1R guidance and note quick wins like antioxidant intake or UV exposure.
Daily longevity stack
- Morning: sunlight exposure, hydration with electrolytes, protein-rich breakfast
- Midday: resistance training or Pilates + fascia release
- Evening: blue-light curfew, magnesium glycinate, journaling to downshift cortisol
Sleep and glycation control keep collagen pliable—protect them ruthlessly.
Regenerative accelerators
After dialling lifestyle basics, add:
1. PRP facelift to reset luminosity and pore texture.
2. Polynucleotide boosters for hydration and barrier repair.
3. Stem cell or exosome infusions when joint or skin damage needs deeper rebuilding.
Document before/after photos every 90 days and align treatments with seasonal stressors (sun, travel, hormonal changes).
INSIGHT
Genetics vs. epigenetics
Genes load the gun; lifestyle pulls the trigger. Here's how to work with both.
MC1R variants
Certain MC1R copies are linked to earlier wrinkling because they produce less eumelanin. Daily SPF and antioxidants counter the oxidative load.
FOXO3 longevity gene
People with FOXO3 variants regulate autophagy better. Mimic the effect with low-glycaemic diets, intermittent fasting, and adequate protein (1.2 g/kg).
Epigenetic age
Inflammation, alcohol, and poor sleep accelerate methylation drift. Focus on anti-inflammatory nutrition and stress management to keep biological age younger than chronological age.
INSIGHT
Lifestyle levers you can control
Everyday choices either protect or degrade collagen.
Glycation control
Aim for 30g+ protein per meal, swap ultra-processed snacks for fibre-rich options, and keep HbA1c below 5.2%. Glycation stiffens collagen and dulls skin.
Sleep & circadian cues
Consistent bedtimes, morning sunlight, and limiting blue light one hour before bed keep cortisol rhythms stable and support nightly repair.
Movement & fascia
Strength training plus facial massage devices keep fascia toned, preventing laxity and heaviness.
INSIGHT
Regenerative treatments that move the needle
When lifestyle is optimised, add targeted medical boosters.
PRP Vampire Facelift
Liquid gold rich in growth factors boosts collagen types I & III, brightens tone, and softens texture for 12–18 months.
Polynucleotide skin boosters
PN strands hydrate deep dermal layers, improve elasticity, and calm redness—ideal for tech neck or dullness.
Stem-cell & exosome infusions
BMAC or adipose stem-cell therapy plus exosomes repair chronic damage in joints and skin, keeping you active and radiant.
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Frequently Asked Questions
Answers straight from our clinical consults