How is Arthrosamid® injection different from hyaluronic acid injections?

Arthrosamid® injection is fundamentally different from hyaluronic acid injections. While hyaluronic acid provides temporary lubrication and typically requires multiple injections over time, Arthrosamid® is a non-biodegradable hydrogel that permanently combines with the synovial lining of your joint. Through a natural filtering process, the synovium uptakes the inert hydrogel, reducing the inflammatory cytokine storm that causes pain and stiffness in osteoarthritis. This provides relief for years rather than months from a single injection.

How long do Arthrosamid® injection results last?

To date, 23,000 patients across the UK and Europe have been treated with Arthrosamid® injection, supported by 4 clinical studies demonstrating multiple years of sustained pain relief. Two of these clinical studies demonstrate sustained pain relief for up to 5 years from a single injection. Because the hydrogel permanently integrates with the synovial membrane, many patients experience sustained relief for several years.

How does Arthrosamid Injection work?

Arthrosamid Injection works by integrating with the synovial membrane, which is the soft tissue lining inside the knee joint. This may help create a cushioning effect within the joint and support improved comfort and movement in suitable patients. Official Arthrosamid and provider sources describe this as a gradual process rather than an instant result.

Who is a suitable candidate for Arthrosamid Injection?

Arthrosamid Injection may be suitable for patients with symptomatic knee osteoarthritis who want a longer-lasting, non-surgical treatment option. Suitability depends on your symptoms, knee condition, imaging findings, medical history, and whether another treatment would be more appropriate.

Is Arthrosamid Injection painful?

The procedure is usually carried out under local anaesthetic, so Arthrosamid Injection is generally well tolerated. Some patients may feel pressure or mild discomfort during or shortly after the injection, but this is usually temporary. Competitor FAQ sections commonly include this question because it is one of the main concerns patients have before booking.

How long does the Arthrosamid Injection procedure take?

Arthrosamid Injection is usually performed as an outpatient procedure and is commonly completed within a short appointment. Provider sources for image-guided joint injections note that these treatments often take around 15 to 30 minutes, although total clinic time may be longer when preparation and aftercare are included.

How soon will I feel relief from Arthrosamid Injection?

Relief from Arthrosamid Injection is usually gradual rather than immediate. Official Arthrosamid information notes that integration into the synovial tissue occurs over several weeks, so patients often notice improvement progressively rather than on the day of treatment.

How long do Arthrosamid Injection results last?

For suitable patients, Arthrosamid Injection is intended to provide long-lasting symptom relief. Official Arthrosamid sources include this as one of the most common patient questions, and provider pages consistently position it as a longer-lasting option compared with short-term injectables.

What should I expect after Arthrosamid Injection?

After Arthrosamid Injection, some patients may notice mild swelling, fullness, aching, or temporary discomfort in the knee. Most patients can return home the same day, and improvement is usually gradual over the following weeks rather than immediate. This is also a key topic covered in the official Arthrosamid FAQ.

Can Arthrosamid Injection be used in both knees?

Official Arthrosamid FAQ materials include whether treatment can be given in both knees as a common patient question. Whether this is suitable depends on your symptoms, examination findings, and imaging review, so this is something that should be decided during consultation.

Why are antibiotics sometimes recommended before Arthrosamid Injection?

The official Arthrosamid FAQ specifically includes why prophylactic antibiotics are recommended. This is part of the treatment protocol used by some providers to reduce infection risk around the procedure. Your clinic should present this according to its own protocol and clinician guidance.

How is Arthrosamid Injection different from hyaluronic acid injections?

Arthrosamid Injection is different because it is designed to integrate with the synovial lining of the knee rather than act as a shorter-term injectable. This is one reason provider pages present Arthrosamid Injection as a longer-lasting option for suitable patients with knee osteoarthritis.

Can Arthrosamid Injection help me avoid knee replacement surgery?

For some suitable patients, Arthrosamid Injection may help manage symptoms well enough to delay the need to consider more invasive treatment, but it is not a guarantee that surgery will never be needed. The answer depends on the severity of knee osteoarthritis and the individual response to treatment.

How safe is Arthrosamid Injection?

Arthrosamid Injection is used in appropriately selected patients after clinical assessment. As with any injection, there can be risks and side effects, which is why your medical history, knee condition, and suitability should always be reviewed before treatment.

What is the best painkiller for knee pain?

There is no single best painkiller for every patient with knee pain. The right option depends on the cause of the pain, your medical history, and any other medicines you take. If knee osteoarthritis is the cause, Arthrosamid Injection may be considered as part of a longer-term treatment plan for suitable patients rather than relying only on short-term pain relief. This exact question also appears on competitor content targeting symptom-led searches.

What causes knee pain in females?

There are many possible causes of knee pain in females, including knee osteoarthritis, patellofemoral pain, meniscal problems, previous injury, inflammatory conditions, and biomechanical factors. Competitor content also targets this search intent by noting that women are more prone to knee osteoarthritis, especially with age and hormonal change.

My knee hurts when I bend it and straighten it. Could it be osteoarthritis?

It could be, but not always. Pain when bending and straightening the knee may be linked to knee osteoarthritis, but it can also happen with cartilage irritation, meniscal problems, swelling, or other joint conditions. A proper assessment is needed before deciding whether Arthrosamid Injection is appropriate. NHS and provider resources both make clear that osteoarthritis commonly causes pain, stiffness, and movement difficulty, but diagnosis still needs clinical review.

What is the fastest way to relieve knee pain?

The fastest short-term relief depends on the cause of the pain. Rest, activity modification, and guided pain relief may help temporarily, but longer-term improvement depends on correct diagnosis and appropriate treatment. If symptoms are ongoing, Arthrosamid Injection may be considered for suitable patients with knee osteoarthritis as a longer-lasting option. Competitor pages are also using this kind of question-led search intent.

Can I combine Arthrosamid Injection with physiotherapy or other treatments?

Yes, in many cases rehabilitation and supportive treatment may still be important. The Arthrosamid professional resources include a rehabilitation programme, which suggests that structured exercise and recovery support can sit alongside treatment planning for appropriate patients.

Arthrosamid Injection London — Knee Osteoarthritis Treatment

Orthopaedic-Led Care, Wimpole Street London

Arthrosamid Injection London — Knee Osteoarthritis Treatment

A single, non-surgical injection for suitable patients with knee osteoarthritis, delivered by an orthopaedic consultant at our Wimpole Street clinic.

Delivered at our CQC-regulated London clinic on Wimpole Street.

Non-Surgical

No incisions · no general anaesthetic

Up To 5 Years

Knee Pain Relief

25+ Years Experience

Dr Syed Nadeem Abbas, MBBS

GMC Registered

CQC regulated · fully insured

Book Your Arthrosamid Consultation

Non-Surgical

No incisions, no general anaesthetic

Up To 5 Years

Knee Pain Relief

25+ Years Experience

Dr Syed Nadeem Abbas, MBBS

GMC Registered

CQC regulated, fully insured

As Featured In

Certified Excellence

Regulated & Accredited

Treatment At A Glance

Quick Treatment Facts

Everything you need to know before booking—timelines, comfort level, and investment.

Results Visible

4-6 weeks

Results Last

Up to 5 years

Anesthesia

Local anaesthetic

Downtime

3-5 days reduced activity

Pain Level

Low to moderate

Duration

30-45 minute procedure

Price

From £2,800

Sessions

Single injection

What Is Arthrosamid Injection?

Arthrosamid Injection is a non-surgical treatment for suitable patients with knee osteoarthritis. It is a non-biodegradable hydrogel made of 97.5% water and 2.5% cross-linked polyacrylamide, injected directly into the knee joint under ultrasound guidance. Unlike short-term options such as steroid or hyaluronic acid injections, Arthrosamid is designed to integrate with the synovial tissue lining the knee rather than simply coating or lubricating it temporarily.

Once injected, the hydrogel is gradually taken up into the synovial membrane through the joint's natural filtering process. Official Arthrosamid materials describe this integration as largely complete within four to six weeks. During this period, the hydrogel may help support joint cushioning, reduce stiffness, and improve comfort in suitable patients. Results are gradual rather than immediate, and individual outcomes vary depending on the severity of the condition and the patient's overall health.

At Dr SNA Clinic, every Arthrosamid Injection is performed by Mr S N Abbas, MBBS, MRCSEd, under ultrasound guidance at our clinic on Wimpole Street, Marylebone. Mr Abbas reviews each patient's imaging, medical history, and symptoms before confirming suitability. This page is informational and does not replace a personalised clinical assessment.

Single injection procedure under ultrasound guidance

Clinical data indicating pain relief may last up to 5 years in suitable patients

Non-biodegradable hydrogel that integrates with the synovial tissue

Improvement typically begins around 4 weeks post-injection

Life after treatment

Getting Back to the Life You Enjoy

For suitable patients, Arthrosamid Injection may help reduce knee pain and support a more active daily life. Results vary between individuals.

Patient walking confidently after Arthrosamid Injection

Everyday activity

Walking further without stopping

Up to 5+

Lasting Relief

Sustained improvements in published clinical studies

Patient comfortable at home after knee treatment

Daily comfort

Stairs, mornings, and everyday movement

Patient enjoying garden after knee osteoarthritis treatment

Getting outside

The garden, the park, the places you avoided

The activities given up and now within reach

Patient at Dr SNA Clinic, London

Find out if Arthrosamid Injection is suitable for you. A consultation with Mr S N Abbas at our Wimpole Street clinic is the first step.

Book Your Consultation

Reclaim Your Active Lifestyle with Arthrosamid Injection

Knee osteoarthritis can make everyday activities feel harder than they should. Pain, stiffness, and reduced movement can affect walking, stairs, exercise, work, and sleep. For many people, including those experiencing knee pain in ladies, these symptoms can gradually begin to affect confidence, independence, and overall quality of life.

For suitable patients, Arthrosamid Injection may help reduce knee pain, ease stiffness, and support better mobility over time. Reputable UK provider sources describe Arthrosamid Injection as a long-lasting, non-surgical option for people with knee osteoarthritis who want to stay active and improve day-to-day comfort.

If knee pain is stopping you from doing the things you enjoy, Arthrosamid Injection may offer a treatment option worth considering after proper assessment. The aim is not just symptom control, but helping suitable patients move with more comfort and confidence in daily life.

Return to Activities

Get back to the hobbies and activities you love with reduced pain and improved mobility.

Lasting Freedom

Experience years of relief from a single treatment, not just months.

Active lifestyle with Arthrosamid treatment

Mechanism of action

How Arthrosamid Works Inside the Knee

Arthrosamid Injection works differently from many other knee injection treatments. According to official Arthrosamid and Contura materials, it is designed to integrate with the synovial membrane, the soft tissue lining inside the knee joint. This integration process is what distinguishes Arthrosamid from shorter-term injectable options for suitable patients with knee osteoarthritis.

Injection Into the Synovial Cavity

After local anaesthetic is applied, the hydrogel is injected directly into the synovial cavity of the knee joint. This may be performed with ultrasound guidance to support accurate placement. It is typically carried out as an outpatient procedure.

Uptake Into the Synovial Membrane

Once inside the joint, the hydrogel disperses within the synovial fluid and is gradually taken up into the synovial membrane through the joint's natural filtering process. Official Arthrosamid materials describe this integration as largely complete within four to six weeks.

Integration Within the Synovial Tissue

As the hydrogel integrates with the synovial tissue, official materials describe increased tissue elasticity and resilience. This may contribute to symptom relief and improved movement in suitable patients over time, although the exact pathways behind pain relief are still being studied.

Longer-Lasting Symptom Support

Because Arthrosamid is non-biodegradable, it is not broken down in the same way as some other injected materials. Published follow-up studies have reported sustained improvements in pain and function for up to 5 years after a single injection in study participants, although individual outcomes vary.

How Arthrosamid compares to other knee injections

Steroid Injections

Used for short-term symptom relief
Effect duration varies between patients
Biodegradable

Hyaluronic Acid

Designed to supplement joint lubrication and viscoelasticity
Broken down by the body over time
Biodegradable

Arthrosamid

Designed to integrate with synovial tissue
Non-biodegradable. Single injection.
Study follow-up data up to 5 years

Single injection

The mechanism described here is based on official Arthrosamid and Contura materials and published clinical study data. Individual results vary depending on the patient's condition, age, and general health. Suitability is always confirmed at consultation with Mr S N Abbas before any treatment is recommended.

Understanding Knee Osteoarthritis

Watch our expert explain common conditions and treatment options in these informative videos.

Presented by

Mr Syed Nadeem Abbas

Expert Orthopaedic Physician

MBBS, MRCSEd, MSc

PART-1

Part 1: What Is Knee Osteoarthritis?

PART-2

Part 2: Why Does Knee Osteoarthritis Hurt?

PART-3

Part 3: Where Does The Pain Really Come From?

PART-4

Part 4: What Is Synovitis?

PART-5

Part 5: How Do You Know If You Have Synovitis?

PART-6

Part 6: Which Stage Of Osteoarthritis Is Synovitis?

PART-7

Part 7: How Arthrosamid Works?

Presented by

Mr Syed Nadeem Abbas

Expert Orthopaedic Physician

MBBS, MRCSEd, MSc

PART-1

Part 1: What Is Knee Osteoarthritis?

PART-2

Part 2: Why Does Knee Osteoarthritis Hurt?

PART-3

Part 3: Where Does The Pain Really Come From?

PART-4

Part 4: What Is Synovitis?

PART-5

Part 5: How Do You Know If You Have Synovitis?

PART-6

Part 6: Which Stage Of Osteoarthritis Is Synovitis?

PART-7

Part 7: How Arthrosamid Works?

Symptoms and conditions

What Knee Symptoms Can Arthrosamid Injection Help With?

Arthrosamid Injection is used for the symptomatic treatment of knee osteoarthritis. It is not a cure for arthritis, and it does not reverse joint damage. For suitable patients, it may help reduce pain, ease stiffness, and support better movement over time. The symptoms below are commonly associated with knee osteoarthritis and are often discussed by patients who enquire about Arthrosamid Injection at our clinic.

Persistent Knee Pain

Pain that continues despite rest, pain relief medication, or physiotherapy. Often described as a deep aching sensation inside or around the knee that worsens with activity or after prolonged sitting.

Morning Stiffness

Stiffness in the knee on waking or after periods of inactivity. NHS guidance notes that joint stiffness is a common symptom of osteoarthritis, particularly in the morning or after rest.

Reduced Mobility and Range of Movement

Difficulty bending, straightening, or fully extending the knee. Many patients describe difficulty with stairs, getting up from a chair, or walking for extended periods.

Swelling Around the Knee

Mild to moderate swelling in or around the knee can occur with osteoarthritis and may contribute to discomfort and reduced function.

Pain on Bending or Straightening

Patients who feel that their knee hurts when they bend it and straighten it may have osteoarthritis as an underlying cause. Proper clinical assessment is needed to confirm this.

Reduced Confidence in Everyday Movement

The anticipation of pain can affect how people walk, exercise, and approach everyday tasks. For some patients, reduced confidence in movement is as significant as the pain itself.

Not all knee pain is caused by osteoarthritis. Mr S N Abbas will review your symptoms, medical history, examination findings, and any available imaging, or arrange investigations if clinically appropriate, before discussing whether Arthrosamid Injection is suitable for you.

Before you decide

What to Expect at Your Consultation

Your consultation with Mr S N Abbas is the essential first step before any decision is made about Arthrosamid Injection. It is not a sales appointment. The purpose is to give you an honest clinical view of whether Arthrosamid Injection is appropriate for your situation.

Review of Your Symptoms and History

Mr S N Abbas will take a detailed history of your knee symptoms, including how long you have had pain, what makes it better or worse, what treatments you have already tried, and how your knee is affecting your daily life and activities.

Assessment of Your Imaging

Where imaging is available, Mr S N Abbas will review it as part of the assessment. NICE guidance states that osteoarthritis is usually diagnosed clinically and does not usually require imaging to confirm the diagnosis. Imaging may still be arranged where clinically appropriate, particularly if there are atypical features or another cause of knee pain needs to be considered.

Discussion of Your Options

Mr S N Abbas will explain what Arthrosamid Injection involves, what the clinical evidence shows, and what outcomes are realistic for your specific situation. He will also discuss alternative treatment options where relevant. If he does not believe Arthrosamid Injection is the right option for you, he will say so clearly.

Your Questions Answered

The consultation is your opportunity to ask anything you need to feel comfortable and informed. There is no obligation to proceed, and no decision needs to be made on the day.

This page is informational and does not replace a personalised clinical assessment. Suitability for Arthrosamid Injection is confirmed at consultation only.

After your treatment

Recovery, Aftercare, and When Results Start

Recovery after Arthrosamid Injection is generally straightforward for most patients. The procedure is carried out as an outpatient treatment, and most people are able to return home the same day. Individual experience varies, and Mr S N Abbas will give you specific aftercare advice before you leave the clinic.

The First Few Days

Some mild discomfort, swelling, or a feeling of fullness in the treated knee is normal and is not a sign that the treatment has not worked. Avoid strenuous activity. Mr S N Abbas will give you specific guidance on activity levels before you leave.

Returning to Normal Activity

Most patients return to light daily activities relatively quickly. Strenuous exercise and high-impact activity should be avoided until Mr S N Abbas advises otherwise. Physiotherapy may be recommended to support recovery and maximise the benefit of treatment.

When to Seek Advice

If you experience significant worsening of pain, signs of infection such as increasing redness, warmth or fever, or any concern that feels out of the ordinary, contact the clinic directly. Do not wait for your follow-up appointment if you are concerned.

When Results Typically Start

Based on official Arthrosamid materials and published clinical study data. Individual outcomes vary considerably.

Week 1 to 2

Settling period

The knee is settling after the injection. Some discomfort or swelling is normal. Most patients notice no significant change in symptoms at this stage.

Week 4

Early changes

The hydrogel integration process is progressing. Some patients begin to notice early changes in comfort or stiffness around this point, though this varies considerably between individuals.

Weeks 8 to 12

Main improvement period

Official Arthrosamid materials describe the integration process as largely complete within four to six weeks. Many patients report the most noticeable improvements in pain, stiffness, and mobility during this period. The follow-up review with Mr S N Abbas is typically scheduled around this time.

12 months and beyond

Sustained results

Published follow-up studies have reported sustained improvements in pain and function for up to five years after a single injection in study participants. Individual outcomes vary. An annual review may be recommended to assess ongoing response to treatment.

Results described here are based on official Arthrosamid materials and published clinical study data. Individual outcomes vary. This information does not replace the personalised aftercare guidance provided by Mr S N Abbas at your appointment.

The Science Behind Arthrosamid Injection

Arthrosamid Injection is a non-biodegradable hydrogel made of 97.5% water and 2.5% polyacrylamide. It is designed for the symptomatic treatment of knee osteoarthritis and works differently from short-term injectable options because it is intended to become integrated within the synovial tissue of the knee.

The science behind Arthrosamid Injection focuses on the synovial membrane, which is the soft tissue lining inside the knee joint. After injection, the hydrogel is taken up into this tissue over time, where it may help create a cushioning effect, support joint elasticity, and improve comfort in suitable patients. Official Arthrosamid and UK provider sources describe this as a gradual physical and biological process rather than an instant effect.

This is why Arthrosamid Injection is often discussed as a longer-lasting option for knee osteoarthritis. Clinical and provider information reports that, in suitable patients, it may help reduce pain, ease stiffness, and improve mobility after a single injection, with benefits that can be maintained over time.

Synovial Integration

Permanently combines with synovial membrane through natural filtering process

Reduces Inflammation

Reduces cytokine storm of inflammatory cells in synovial lining

Proven Longevity

2 clinical studies showing sustained relief for up to 5 years from single injection

Extensive Clinical Use

Over 23,000 patients treated with support from multiple clinical trials

Medical illustration of Arthrosamid hydrogel integrating with knee synovial membrane

Patient Information

Download official Arthrosamid® materials for more detailed information

Download Leaflet Download Brochure

EXPERT PERSPECTIVE

A Game-Changer in Knee Osteoarthritis Management

Understanding Arthrosamid Injection’s unique mechanism of action

For many patients, living with knee osteoarthritis means managing ongoing pain, stiffness, and reduced mobility with temporary measures that do not always provide lasting relief. This is why Arthrosamid Injection has become an important non-surgical option for suitable patients looking for longer-term support. If knee pain is affecting your walking, daily routine, or confidence in movement, Arthrosamid Injection may offer a different approach to treatment.

What makes Arthrosamid Injection different is the way it works inside the joint. Rather than acting as a short-term injectable, Arthrosamid Injection is a non-biodegradable hydrogel designed to integrate with the synovial membrane in the knee. Over time, this may help support the joint environment, reduce stiffness, and improve comfort and function in suitable patients. This is one reason why Arthrosamid Injection is increasingly discussed as a longer-lasting option for knee osteoarthritis management.

For patients comparing treatment choices, Arthrosamid Injection may be appealing because it is a single-injection, non-surgical treatment that fits between repeated short-term injections and more invasive procedures. Patients researching Arthrosamid Injection Cost or Arthrosamid Injection Cost UK are often looking not only at price, but also at durability, convenience, and whether the treatment may help them stay active for longer. For suitable patients, Arthrosamid Injection may support longer-lasting symptom relief and help improve day-to-day mobility.

Single Injection Protocol

A one-time Arthrosamid Injection treatment designed for suitable patients with knee osteoarthritis.

Non-Surgical Solution

Arthrosamid Injection may help suitable patients manage symptoms without moving straight to surgery.

Synovial Integration

The hydrogel is designed to integrate with the synovial membrane, which may help support joint comfort and function over time.

Proven Safety Profile

Arthrosamid Injection is used as a clinically assessed treatment option for appropriately selected patients.

Dr. S.N. Abbas - Consultant expert in regenerative pain management

Over 25 years of expertise in regenerative pain management and interventional procedures

Why patients choose Arthrosamid

Key Benefits of Arthrosamid Injection

Based on official Arthrosamid and Contura materials and published clinical study data. Suitable patients only. Individual results vary. Suitability confirmed at consultation.

Single injection

One treatment rather than a course of repeated appointments

5yr

Study follow-up data

Sustained improvements reported in published clinical studies

General anaesthetic

Outpatient procedure under local anaesthetic only

Non-biodegradable hydrogel

Designed to remain in the synovial tissue rather than being absorbed over time, according to official Contura materials.

May Help Some Patients Postpone Further Intervention

For some suitable patients, Arthrosamid Injection may help manage symptoms well enough to postpone the need to consider more invasive options. This is not guaranteed and depends on the individual patient's condition and response to treatment.

Same-Day Discharge

Most patients are able to return home on the same day without an overnight stay. Mild discomfort or swelling in the days following is common as the knee settles.

Benefits described here are based on official Arthrosamid and Contura materials and published clinical data. They do not constitute a guarantee of results. Suitability for Arthrosamid Injection is confirmed following clinical assessment with Mr S N Abbas.

How It Works

Your Arthrosamid® Injection Journey

Step 1

1 of 5

Consultation & Assessment

Comprehensive evaluation including imaging review to confirm you're a suitable candidate for Arthrosamid® treatment.

Honest comparison

Arthrosamid vs Other Knee Injection Options

Patients researching knee osteoarthritis treatment often consider several injection options before making a decision. The comparison below is based on published clinical guidance including NICE, official Arthrosamid and Contura materials, and reputable UK provider sources. It is intended to help you understand the differences, not to suggest that one treatment is always superior to another. The right option depends on your specific diagnosis, medical history, and clinical assessment with Mr S N Abbas.

Treatment	How it works	Duration of effect	Injections	Downtime
Arthrosamid Available here Selected adults with knee osteoarthritis after clinical assessment	Integrates with synovial tissue. Non-biodegradable hydrogel. Based on official Arthrosamid and Contura materials.	Up to 5 years in published follow-up studies in study participants.	Single injection	Minimal. Reduced activity for a few days.
Steroid Injection Short-term relief	Reduces inflammation temporarily. Corticosteroid injection.	Around 2 to 10 weeks per NICE guidance.	Repeated as needed	Minimal
Hyaluronic Acid Not NICE recommended NICE advises not to offer intra-articular hyaluronan injections for osteoarthritis management.	Designed to supplement joint lubrication and viscoelasticity. Biodegradable.	Months. Variable between patients.	1 to 3 typically	Minimal
PRP Injection Limited evidence quality	Uses growth factors from the patient's own blood. Autologous treatment.	Variable. NICE notes evidence on efficacy is limited in quality. Use requires special arrangements for governance, consent, and audit or research.	Typically 1 to 3 sessions	Minimal
Knee Replacement Surgical	Surgical replacement of the damaged joint. General or spinal anaesthetic.	15 to 20 years typically.	Surgery required	Significant. Weeks to months.

Arthrosamid

Available here

How it works

Integrates with synovial tissue. Non-biodegradable hydrogel. Based on official Arthrosamid and Contura materials.

Duration

Up to 5 years in published follow-up studies in study participants.

Injections

Single injection

Downtime

Minimal. Reduced activity for a few days.

Selected adults with knee osteoarthritis after clinical assessment

Steroid Injection

Short-term relief

How it works

Reduces inflammation temporarily. Corticosteroid injection.

Duration

Around 2 to 10 weeks per NICE guidance.

Injections

Repeated as needed

Downtime

Minimal

Hyaluronic Acid

Not NICE recommended

How it works

Designed to supplement joint lubrication and viscoelasticity. Biodegradable.

Duration

Months. Variable between patients.

Injections

1 to 3 typically

Downtime

Minimal

NICE advises not to offer intra-articular hyaluronan injections for osteoarthritis management.

PRP Injection

Limited evidence quality

How it works

Uses growth factors from the patient's own blood. Autologous treatment.

Duration

Variable. NICE notes evidence on efficacy is limited in quality. Use requires special arrangements for governance, consent, and audit or research.

Injections

Typically 1 to 3 sessions

Downtime

Minimal

Knee Replacement

Surgical

How it works

Surgical replacement of the damaged joint. General or spinal anaesthetic.

Duration

15 to 20 years typically.

Injections

Surgery required

Downtime

Significant. Weeks to months.

This comparison is for informational purposes only and does not constitute clinical advice. Guidance references include NICE and official Arthrosamid and Contura materials. The most appropriate treatment depends on individual clinical assessment. Mr S N Abbas will discuss all relevant options at your consultation and give you an honest view of which approach is most suitable for your situation.

Patient safety

Safety, Side Effects, and Risks of Arthrosamid Injection

Arthrosamid Injection is generally considered a low-risk, minimally invasive procedure when carried out by an appropriately trained clinician in a suitable clinical setting. As with any injectable treatment, there are potential side effects and risks that patients should understand before making a decision. All risks and contraindications are discussed with Mr S N Abbas at consultation before any treatment is agreed.

Common side effects

Pain or discomfort at the injection site

Mild to moderate pain or discomfort in the knee in the days following the procedure. Common and expected. Typically resolves within a few days.

Swelling and joint effusion

Mild swelling or a feeling of fullness in the knee is commonly reported. Generally settles without treatment. Contact the clinic if swelling is significant or worsening.

Temporary stiffness

Some patients notice temporary increased stiffness in the treated knee in the days following the procedure. Typically improves as the knee settles.

Bruising

Minor bruising around the injection site may occur and is not a cause for concern in most cases.

Less common or serious risks

Infection

Infection is a rare but serious risk associated with any invasive joint procedure. Because of this risk, Arthrosamid is administered under sterile conditions and official product instructions state that prophylactic antibiotics should be given before injection. If you experience increasing redness, warmth, fever, or worsening pain after the procedure, seek medical attention promptly and contact the clinic directly.

Hypersensitivity and allergic reaction

Patients with a known hypersensitivity to polyacrylamide or any component of the treatment should not receive Arthrosamid. Any relevant allergies, previous reactions to injected treatments, antibiotics, or local anaesthetic should be discussed at consultation before the procedure is agreed.

No improvement in symptoms

Not all patients respond to Arthrosamid Injection. Outcomes vary between individuals and a meaningful improvement is not guaranteed. Mr S N Abbas will give you a realistic assessment of the likelihood of benefit based on your specific situation.

Treatment not suitable after review

Following consultation and clinical review, Mr S N Abbas may advise that Arthrosamid Injection is not the most appropriate option for your knee. Alternative treatment options will be discussed openly.

How we protect patient safety

Every procedure performed by Mr S N Abbas, MBBS, MRCSEd

CQC Regulated Clinic

GMC Registered Physician

Sterile single-use equipment

Full risk discussion at consultation

Written aftercare provided

This section is informational and is not a complete list of all possible risks or contraindications. All risks and benefits are discussed in full at your consultation with Mr S N Abbas before any treatment is agreed. If you have specific concerns about safety or contraindications, raise them at consultation or contact the clinic directly.

Published evidence

The Clinical Evidence Behind Arthrosamid Injection

Arthrosamid Injection is supported by clinical study data published in peer-reviewed journals. Where evidence is limited or still developing, this is stated clearly. This section is intended to help patients make an informed decision and does not constitute a guarantee of results.

RCT

Study design

Randomised controlled trial vs hyaluronic acid

5yr

Follow-up data

Prospective extension study 2025

97.5%

Water content

Non-biodegradable hydrogel

20,000+

Patients treated

Per official Arthrosamid messaging January 2026

Randomised controlled trial

RCT vs Hyaluronic Acid

A published randomised controlled trial compared Arthrosamid Injection with hyaluronic acid in patients with knee osteoarthritis. The study found Arthrosamid was non-inferior to hyaluronic acid over 12 months after a single injection, with clinically meaningful improvements in pain and function reported in the Arthrosamid group. Individual outcomes varied between participants.

Long-term data

Five-Year Follow-Up Data

A 2025 publication reporting five-year follow-up data from a prospective open-label study found sustained improvements in WOMAC pain, stiffness, function, and patient global assessment through to five years in study participants. Individual outcomes varied and further research is ongoing.

Safety profile

Safety in Published Studies

The published clinical data reports a generally favourable safety profile in study participants. The most commonly reported adverse events were procedure-related, such as temporary pain or swelling. In the five-year extension study, no serious events were attributed to the investigational device, and no new adverse device effects were reported.

Important context

Limitations of the Evidence

The evidence base for Arthrosamid Injection is growing but remains relatively limited compared to more established treatments. Published studies involve selected patient populations and controlled settings. Results in a study population may not reflect outcomes for every individual patient in routine clinical practice. Suitability is always assessed individually by Mr S N Abbas.

The evidence summaries above are based on official Arthrosamid and Contura materials and published peer-reviewed data available at the time of writing. Individual results vary. This information does not replace a personalised clinical assessment with Mr S N Abbas.

Your consultant

Meet Mr Syed Nadeem Abbas

Mr Syed Nadeem Abbas

MBBS · MRCSEd · MSc (Distinction)

Medical Director, Dr SNA Clinic

4.9

36 verified Google reviews

MRCSEd

Royal College of Surgeons, Edinburgh

MSc Distinction

Queen Mary University of London

GMC Registered

General Medical Council

CQC Regulated Clinic

Care Quality Commission

American Cellular Medical Association

Arthrosamid specialist certification

NHS Cambridge and Oxford

6+ years Trauma and Orthopaedics

10,000+ patients treated

Patients from 90+ countries

Every Arthrosamid Injection at Dr SNA Clinic is performed by Mr Syed Nadeem Abbas personally, from the pre-injection assessment through to the procedure itself. He does not delegate this treatment. Understanding his background helps explain why patients choose to travel to our Wimpole Street clinic from across the UK and internationally.

Surgical Foundation - NHS Trauma and Orthopaedics

Mr S N Abbas built his clinical career on over six years in Trauma and Orthopaedics at major NHS hospitals including Cambridge and Oxford. This level of training demands precise anatomical knowledge and procedural discipline, both of which directly inform his approach to joint injection therapy today.

Academic Distinction - Queen Mary University of London

Mr S N Abbas completed his postgraduate Masters in Aesthetic Plastic Surgery at Queen Mary University of London, graduating with Distinction. He is also a Member of the Royal College of Surgeons of Edinburgh (MRCSEd), achieved in 2006.

Arthrosamid Specialist Training - American Cellular Medical Association

His specialist training in Arthrosamid and regenerative joint injection therapy was completed through the American Cellular Medical Association, making Mr S N Abbas one of a small number of UK-based clinicians with formal certification in this specific area.

His Approach to Consultation

In consultation, Mr S N Abbas is known for being direct and unhurried. He will not recommend a treatment he does not believe is clinically appropriate, and he will tell you plainly if Arthrosamid Injection is unlikely to help in your case. There is no pressure and no hard sell. That is not how he practises.

Full profile, credentials and patient reviews

View Dr S N Abbas full profile

What Patients Say About Knee Treatment at Dr SNA Clinic

Verified reviews from patients who have undergone knee treatment at Dr SNA Clinic, London

Google Reviews4.9

Trustpilot4.2

Knee Treatment

Google

"I really felt listened to. Great care. I had stem cells in my knee. I thought I would be in severe pain when harvesting the bone marrow from my pelvis, but the local anaesthetic was so good I did not feel a thing. Very impressed. A lovely team.

Claire Tanner

Knee Treatment

Verified

Knee Treatment

Google

"I visited SNA Clinic for severe knee pain, and Dr Abbas was fantastic. He explained everything clearly and recommended a treatment plan that worked within weeks. I am finally walking without pain again.

Fawad Bhatti

Knee Pain Treatment

Verified

Knee Treatment

Google

"The knee treatment was highly effective, and I have noticed a significant reduction in pain and improved mobility. The care and professionalism of the team were outstanding throughout the process.

Muhammad Ahsan

Knee Treatment

Verified

Knee Treatment

Google

"I have pain in my left knee. The doctor suggested PRP of knee and I followed the instructions. Now after treatment I am completely recovered and satisfied from this doctor.

Muhammad U.

Knee PRP Treatment

Verified

Knee Treatment

Google

"Amazing customer service. Solved my knee problem.

Wind Eye

Knee Treatment

Verified

Trustpilot

"The service was so seamless and exactly what I expected. Dr Abbas was generally nice and I enjoyed his service.

Ekene F.

Dr SNA Clinic

Verified

Trustpilot

"Great experience from Dr SNA Clinic. From the initial enquiry through to the treatment, all 10 out of 10. I would recommend.

Matt G.

Dr SNA Clinic

Verified

Knee Treatment

Google

Claire Tanner

Knee Treatment

Verified

Knee Treatment

Google

Fawad Bhatti

Knee Pain Treatment

Verified

Knee Treatment

Google

"The knee treatment was highly effective, and I have noticed a significant reduction in pain and improved mobility. The care and professionalism of the team were outstanding throughout the process.

Muhammad Ahsan

Knee Treatment

Verified

Knee Treatment

Google

"I have pain in my left knee. The doctor suggested PRP of knee and I followed the instructions. Now after treatment I am completely recovered and satisfied from this doctor.

Muhammad U.

Knee PRP Treatment

Verified

Knee Treatment

Google

"Amazing customer service. Solved my knee problem.

Wind Eye

Knee Treatment

Verified

Trustpilot

"The service was so seamless and exactly what I expected. Dr Abbas was generally nice and I enjoyed his service.

Ekene F.

Dr SNA Clinic

Verified

Trustpilot

"Great experience from Dr SNA Clinic. From the initial enquiry through to the treatment, all 10 out of 10. I would recommend.

Matt G.

Dr SNA Clinic

Verified

Knee Treatment

Google

Claire Tanner

Knee Treatment

Verified

Knee Treatment

Google

Fawad Bhatti

Knee Pain Treatment

Verified

Knee Treatment

Google

"The knee treatment was highly effective, and I have noticed a significant reduction in pain and improved mobility. The care and professionalism of the team were outstanding throughout the process.

Muhammad Ahsan

Knee Treatment

Verified

Knee Treatment

Google

"I have pain in my left knee. The doctor suggested PRP of knee and I followed the instructions. Now after treatment I am completely recovered and satisfied from this doctor.

Muhammad U.

Knee PRP Treatment

Verified

Knee Treatment

Google

"Amazing customer service. Solved my knee problem.

Wind Eye

Knee Treatment

Verified

Trustpilot

"The service was so seamless and exactly what I expected. Dr Abbas was generally nice and I enjoyed his service.

Ekene F.

Dr SNA Clinic

Verified

Trustpilot

"Great experience from Dr SNA Clinic. From the initial enquiry through to the treatment, all 10 out of 10. I would recommend.

Matt G.

Dr SNA Clinic

Verified

Knee Treatment

Google

Claire Tanner

Knee Treatment

Verified

Knee Treatment

Google

Fawad Bhatti

Knee Pain Treatment

Verified

Knee Treatment

Google

"The knee treatment was highly effective, and I have noticed a significant reduction in pain and improved mobility. The care and professionalism of the team were outstanding throughout the process.

Muhammad Ahsan

Knee Treatment

Verified

Knee Treatment

Google

"I have pain in my left knee. The doctor suggested PRP of knee and I followed the instructions. Now after treatment I am completely recovered and satisfied from this doctor.

Muhammad U.

Knee PRP Treatment

Verified

Knee Treatment

Google

"Amazing customer service. Solved my knee problem.

Wind Eye

Knee Treatment

Verified

Trustpilot

"The service was so seamless and exactly what I expected. Dr Abbas was generally nice and I enjoyed his service.

Ekene F.

Dr SNA Clinic

Verified

Trustpilot

"Great experience from Dr SNA Clinic. From the initial enquiry through to the treatment, all 10 out of 10. I would recommend.

Matt G.

Dr SNA Clinic

Verified

Google Reviews

4.9

36 reviews

Trustpilot

4.2

6 reviews

Book Your Consultation

Transparent pricing

Arthrosamid Injection Cost in London

We publish our pricing openly because patients deserve to know the cost of treatment before they commit to a consultation. The prices below are all-inclusive. There are no hidden fees and no surprises.

Single Knee

Arthrosamid Injection ? One Knee

Arthrosamid Injection for one knee. Includes enhanced recovery support with post-injection physio guidance and supplement advice.

Was £3,200

£2,800

Single knee treatment

Enhanced recovery support included

Enquire About Single Knee

Both Knees

Arthrosamid Injection ? Both Knees

Arthrosamid Injection for both knees. May be considered for suitable patients with symptoms affecting both knees, following proper assessment and imaging review.

Was £6,400

£5,300

Dual knee treatment

Enhanced recovery support included

Enquire About Both Knees

Every treatment includes

Comprehensive consultation with Mr S N Abbas

Ultrasound-guided Arthrosamid injection

Follow-up assessment and ongoing support

Consultation Fee

£100

Redeemable against treatment cost if you proceed

No obligation to proceed at consultation. Treatment cost confirmed before any decision is made.

0% Finance Available

Flexible payment plans to spread the cost. No obligation to apply.

Enquire About Finance

Prices correct at time of publication. All treatment costs confirmed at consultation. Suitability for Arthrosamid Injection is confirmed following clinical assessment with Mr S N Abbas. There is no obligation to proceed.

Patient suitability

Who Is Arthrosamid Injection Suitable For?

Arthrosamid Injection is intended for suitable patients with symptomatic knee osteoarthritis. A thorough consultation and imaging review with Mr S N Abbas is the only way to confirm whether it is the right option for your situation. The information below gives a general guide to who may and may not be considered.

May be suitable if you

Have confirmed knee osteoarthritis
Patients with mild to moderate knee osteoarthritis experiencing pain and stiffness that affects daily life.
Tried simpler measures without relief
Those who have already tried physiotherapy, weight management, or pain relief without sufficient benefit.
Seeking a non-surgical option
Patients who want to explore a non-surgical approach before considering more invasive procedures.
Pain affecting daily activities
People whose knee pain is limiting walking, stairs, exercise, sleep, or everyday comfort.
Limited benefit from short-term injections
Patients for whom steroid or hyaluronic acid injections have provided only limited or temporary benefit.

May not be suitable if you

Have an allergy to polyacrylamide
Patients with a known allergy to polyacrylamide or any component of the hydrogel are not suitable candidates.
Have an active knee infection
Arthrosamid Injection is not suitable where there is an active infection in or around the knee joint.
Have had recent knee surgery
Patients who have undergone recent knee surgery may not be suitable candidates at that time.
Have severe structural joint damage
Where joint damage is advanced, another treatment may be more clinically appropriate. Mr S N Abbas will advise accordingly.
Have a different cause of knee pain
Not all knee pain is caused by osteoarthritis. If another condition is the primary cause, a different approach may be more suitable.

A proper consultation and imaging review are essential before any decision is made. Mr S N Abbas will give you a clear and honest assessment of whether Arthrosamid Injection is appropriate for your knee and your circumstances.

FAQ

Frequently Asked Questions

Everything you need to know about our treatments

Arthrosamid® injection takes 4-6 weeks and out to 3 months to have a clinical effect. This is a physical, biological process. Once the inert hydrogel is injected via ultrasound, the natural filtering process of the synovium uptakes the hydrogel, becoming integrated over time. This reduces inflammation and stiffness while improving elasticity of the joint, with many patients experiencing progressive improvements in pain and function during this integration period.

Take the First Step Towards Pain-Free Living

Book a consultation with Dr S N Abbas to assess your suitability for Arthrosamid® treatment and discuss your personalized treatment plan.

Book ConsultationClick Here Request a call backClick Here

4.9

36 reviews on Google Reviews

4.2

6 reviews on Trustpilot

Trusted by patients across the UK